2024
- Yue Zhang, Vanthana Bharathi, Tatsuya Dokoshi, Jaime de Anda, Lauryn Tumey Ursery, Nikhil N. Kulkarni, Yoshiyuki Nakamura, Jonathan Chen, Elizabeth W. C. Luo, Lamei Wang, Hua Xu, Alison Coady, Raymond Zurich, Michelle W. Lee, Tsutomu Matsui, HongKyu Lee, Liana C. Chan, Athena A. Schepmoes, Mary S. Lipton, Rui Zhao, Joshua N. Adkins, Geremy C. Clair, Lance R. Thurlow, Jonathan C. Schisler, Matthew C. Wolfgang, Robert S. Hagan, Michael R. Yeaman, Thomas M. Weiss, Xinhua Chen, Melody M. H. Li, Victor Nizet, Silvio Antoniak, Nigel Mackman, Richard L. Gallo, Gerard C. L. Wong. Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2300644120. doi: 10.1073/pnas.2300644120.
- Serina Huang, Juliana Girdner, LeAnn P. Nguyen, David Enard, Melody M. H. Li. Positive selection analyses identify a single WWE domain residue that shapes ZAP into a super restriction factor. bioRxiv 2023.11.20.567784; doi: https://doi.org/10.1101/2023.11.20.567784
- Zhenlan Yao, Sangeetha Ramachandran, Serina Huang, Yasaman Jami-Alahmadi, James A. Wohlschlegel, Melody M. H. Li. Chikungunya virus glycoproteins transform macrophages into productive viral dissemination vessels. bioRxiv 2023.05.29.542714; doi: https://doi.org/10.1101/2023.05.29.542714
- LeAnn P. Nguyen, Kelly S. Aldana, Emily Yang, Zhenlan Yao, Melody M. H. Li. Alphavirus Evasion of Zinc Finger Antiviral Protein (ZAP) Correlates with CpG Suppression in a Specific Viral nsP2 Gene Sequence. Viruses. 2023; 15(4): 830.
- Emily Yang, Serina Huang, Yasaman Jami-Alahmadi, Gerald M. McInerney, James A. Wohlschlegel, Melody M. H. Li. Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes. PLoS Pathogens. 2022; 18(9): e1010743.
- Jesus Campagna, Barbara Jagodzinsk, Pablo Alvarez, Constance Yeun, Patricia Spilman, Kathryn M. Enquist, Whitaker Cohn, Pavla Fajtová, Anthony J. O'Donoghue, Vaithilingaraja Arumugaswami, Melody M. H. Li, Robert Damoiseaux, John Varghese. Identification of a Papain-Like Protease Inhibitor with Potential for Repurposing in Combination with an Mpro Protease Inhibitor for Treatment of SARS-CoV-2. bioRxiv. 2022;
- Emily Yang, LeAnn P. Nguyen, Carlyn A. Wisherop, Ryan L. Kan, Melody M. H. Li. The Role of ZAP and TRIM25 RNA Binding in Restricting Viral Translation. Frontiers in Cellular and Infection Microbiology. 2022; Sec.Microbes and Innate Immunity.
- Yichen Cheng, Angelica Medina, Zhenlan Yao, Mausumi Basu, Janhavi P. Natekar, Jianshe Lang, Egan Sanchez, Mezindia B. Nkembo, Chongchong Xu, Xuyu Qian, Phuong T. T. Nguyen, Zhexing Wen, Hongjun Song, Guo-Li Ming, Mukesh Kumar, Margo A. Brinton, Melody M. H. Li, Hengli Tang. Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model. Cell Reports. 2022; 39(9): 110885.
- Luu Anh Phuong, Yao Zhenlan, Ramachandran Sangeetha, Azzopardi Stephanie A, Miles Linde A, Schneider William M, Hoffman H-Heinrich, Bozzacco Leonia, Garcia Gustavo, Gong Danyang, Damoiseaux Robert, Tang Hengli, Morizona Kouki, Rudin Charles M, Sun Ren, Arumugaswami Vaithilingaraja, Poirier John T, MacDonald Margaret R, Rice Charles M, Li Melody M H. A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry. Viruses. 2021; 13(11): 2113.
- Yang Emily, Li Melody M H. All About the RNA: Interferon-Stimulated Genes That Interfere With Viral RNA Processes. Frontiers in Immunology. 2020; Sec.Cytokines and Soluble Mediators in Immunity.
- Garcia Gustavo, Paul Sayan, Beshara Sara, Ramanujan V Krishnan, Ramaiah Arunachalam, Nielsen-Saines Karin, Li Melody M H, French Samuel W, Morizono Kouki, Kumar Ashok, Arumugaswami Vaithilingaraja. Hippo Signaling Pathway Has a Critical Role in Zika Virus Replication and in the Pathogenesis of Neuroinflammation. The American Journal of Pathology. 2020; 190(4): 844-861.
- Li Melody M H, Aguilar Eduardo G, Michailidis Eleftherios, Pabon Jonathan, Park Paul, Wu Xianfang, de Jong Ype P, Schneider William M, Molina Henrik, Rice Charles M, MacDonald Margaret R. Characterization of novel splice variants of zinc finger antiviral protein (ZAP). Journal of Virology. 2019; 00715-19.
- Law Lok M J, Razooky Brandon S, Li Melody M H, You Shihyun, Jurado Andrea, Rice Charles M, MacDonald Margaret R. ZAP’s stress granule localization is correlated with its antiviral activity and induced by virus replication. PLoS Pathogens. 2019; 15(5): e1007798.
- X. Wu, V. L. Dao Thi, Y. Huang, E. Billerbeck, D. Saha, H. H. Hoffmann, Y. Wang, L. Vale-Silva, S. Sarbanes, T. Sun, L. Andrus, Y. Yu, C. Quirk, M. M. Li, M. R. MacDonald, W. M. Schneider, X. An, B. R. Rosenberg, and C. M. Rice. 2018. Intrinsic immunity shapes viral resistance of stem cells. Cell. 2018; 172(3): 172:423-438.e25.
- Li Melody M H, Lau Zerlina, Cheung Pamela, Aguilar Eduardo G, Schneider William M, Bozzacco Leonia, Molina Henrik, Buehler Eugen, Takaoka Akinori, Rice Charles M, Felsenfeld Dan P, MacDonald Margaret R TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP). PLoS Pathogens. 2017; 13(1): e1006145.
- Li Melody M H, Bozzacco Leonia, Hoffmann Hans-Heinrich, Breton Gaelle, Loschko Jakob, Xiao Jing W, Monette Sebastien, Rice Charles M, MacDonald Margaret R Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. The Journal of Experimental Medicine. 2016; 213(13): 2931-2947.
- Wang Xinlu, Li Melody M H, Zhao Jing, Li Shenglan, MacDonald Margaret R, Rice Charles M, Gao Xiang, Gao Guangxia Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance. Journal of Virology. 2016; 90(22): 10247-10258.
- Li Melody M H, MacDonald Margaret R Polyamines: Small Molecules with a Big Role in Promoting Virus Infection. Cell Host & Microbe. 2016; 20(2): 123-4.
- Bozzacco Leonia, Yi Zhigang, Andreo Ursula, Conklin Claire R, Li Melody M H, Rice Charles M, MacDonald Margaret R Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication. Journal of Virology. 2016; 90(6): 3212-28.
- Li Melody M H, MacDonald Margaret R, Rice Charles M To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes. Trends in Cell Biology. 2015; 25(6): 320-9.
- Charron Guillaume, Li Melody M H, MacDonald Margaret R, Hang Howard C Prenylome profiling reveals S-farnesylation is crucial for membrane targeting and antiviral activity of ZAP long-isoform. Proceedings of the National Academy of Sciences of the United States of America. 2013; 110(27): 11085-90.
- Karki Sophiya, Li Melody M H, Schoggins John W, Tian Suyan, Rice Charles M, MacDonald Margaret R Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity. PloS One. 2012; 7(5): e37398.
- Li Melody M H, Emerman Michael Polymorphism in human APOBEC3H affects a phenotype dominant for subcellular localization and antiviral activity. Journal of Virology. 2011; 85(16): 8197-207.
- Li Melody M H, Wu Lily I, Emerman Michael The range of human APOBEC3H sensitivity to lentiviral Vif proteins. Journal of Virology. 2010; 84(1): 88-95.
- OhAinle Molly, Kerns Julie A, Li Melody M H, Malik Harmit S, Emerman Michael Antiretroelement activity of APOBEC3H was lost twice in recent human evolution. Cell Host & Microbe. 2008; 4(3): 249-59.